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Knowledge Base
Guides on supplements, nutrition and the research behind them, written in plain language.
Showing 27 results: methylation All Articles
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B Vitamins for Athletes: The Cellular Energy Boost You're Missing
I was wrong about B vitamins for years. Here's what the research shows about optimizing cellular energy conversion for sports performance.
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Betaine for Weight Loss: What the Liver Research Actually Shows
A dietitian breaks down the science behind betaine (TMG) for liver function and fat metabolism—with specific dosing, brand recommendations, and realis...
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Vitamin B6 for Heart Health: The Homocysteine Connection
Learn how vitamin B6 lowers homocysteine to reduce heart disease risk. Get dosing tips, research-backed facts, and my clinical recommendations.
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Folate vs Folic Acid: Why Your Prenatal Might Be Wrong
If you're taking folic acid with MTHFR variations, you might be wasting money. Dr. Amanda Foster explains methylation, gene testing, and which form ac...
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L-Methylfolate for Depression: How This Active Folate Crosses Your Blood-Brain Barrier
A CNS explains how L-methylfolate uniquely supports neurotransmitter production for mood regulation, with dosing guidance and who should avoid it.
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Methylated B Vitamins: Why Your Genetics Matter More Than Your Multivitamin
Most people waste money on wrong B vitamins. Learn how MTHFR and COMT genes affect methylation and which methylated forms (like methylcobalamin) actua...
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Genetic Testing for B Vitamins: Are You Wasting Your Money?
Most people with MTHFR mutations don't need methylated B vitamins. Learn when genetic testing matters, what research shows, and how to supplement smar...
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B Vitamins for Stress: How Your Adrenals Use Them (And What to Take)
Feeling wired and tired? A 2023 study found stressed adults had 40% lower B6 levels. Learn which B vitamins support your adrenals and nervous system n...
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B Vitamins: The Truth About Energy, Stress, and Metabolism
Feeling tired or stressed? B vitamins might help—or waste your money. An RDN breaks down the research, dosing, and what actually works.
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B Vitamins Work Best Together: Why Taking Just One Rarely Helps
That B12 shot alone won't fix your fatigue. Learn why all eight B vitamins work as a team for energy, stress, and brain function—and which complex I a...
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B-Vitamins for Brain Fog: Why Methylation Matters More Than You Think
I used to recommend B-complex to everyone with brain fog—until I saw patients getting worse. Here's what actually works for cognitive support without...
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B-Vitamin Nootropics: Why They're Not Brain Stimulants
I used to recommend B-vitamin stacks for everyone with brain fog—until I saw patients getting anxious and wired. Here's what changed my mind about met...
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Your B-Complex Is Probably Wrong for Mood Support
Most B-complex supplements miss the mark for neurotransmitter support. Learn which specific B-vitamins actually drive serotonin and dopamine productio...
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Why I Stopped Prescribing B6 for Everyone's Heart Health
I used to recommend B6 supplements to every patient with high homocysteine—until I saw the data. Here's what actually works for cardiovascular protect...
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Why I Switched from Pyridoxine to P5P for Homocysteine Control
I used to recommend standard B6—until I saw the data on active P5P. Here's why I changed my mind about lowering homocysteine and what you should take...
